Publications

Fanara S, Schloesser M, Gérard M, De Franco S, Vandevenne M, Vanden Broeck A, Kerff F, Galleni M, Farnir F, Hanikenne M, Motte P. The RNA Recognition Motif (RRM) of the Arabidopsis RS2Z32 and RS2Z33 splicing factors coordinates protein-protein and protein-RNA interactions, and contributes to their nucleocytoplasmic dynamics. (2025) Journal of Experimental Botany, eraf304.

Vanden Broeck A & Klinge S. Eukaryotic ribosome assembly. (2024) Annual Review of Biochemistry, 93:189–210

Vanden Broeck A* & Klinge S*. Principles of human pre-60S biogenesis. (2023) Science 381, eadh3892. Rockefeller press release
Sanghai Z, Piwowarczyk R, Vanden Broeck A, Klinge S. A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation. (2023) Nat Struct Mol Biol, 30, 594–599
Singh S, Banerjee A, Vanden Broeck A, Klinge S. Rapid clonal identification of biallelic CRISPR/Cas9 knock-ins using SNEAK PEEC. (2023) Scientific Reports. 13, 1719.

Wasmuth EV, Vanden Broeck A, LaClair JR, Hoover EA, Lawrence KE, Paknejad N, Pappas K, Matthies D, Wang B, Feng W, Watson PA, Zinder JC, Karthaus WR, de la Cruz JM, Hite JK, Manova-Todorova K, Yu Z, Weintraub ST, Klinge S, Sawyers CL. Allosteric interactions prime androgen receptor dimerization and activation. (2022) Molecular Cell 82 (11), 2021-2031. MSKCC press release
Vanden Broeck A & Klinge S. An emerging mechanism for the maturation of the Small Subunit Processome. (2022) Current Opinion in Structural Biology Vol. 73, 102331
Zhu C, Guo X, Dumas P, Takacs M, Abdelkareem M, Vanden Broeck A, Saint-André C, Papai G, Crucifix C, Ortiz J, Weixlbaumer A. Transcription factors modulate RNA polymerase conformational equilibrium. (2022) Nature Communications. 13 (1546), 1-12

Singh S †, Vanden Broeck A †*, Miller L, Chaker-Margot M, Klinge S*. Nucleolar maturation of the human small subunit processome. (2021) Science 373, eabj5338. Rockefeller press release
Vanden Broeck A, Lotz C, Drillien R, Haas L, Bedez C, Lamour V. Structural basis for allosteric regulation of Human Topoisomerase IIa. (2021) Nature Communications 12 (2962), 1-13
Huang Shar-yin N, Michaels SA, Mitchell BB, Majdalani N, Vanden Broeck A, Canela A, Tse-Dinh YC, Lamour V, Pommier Y. Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes. (2021) Science Advances 7 (10), eabe0384

Vanden Broeck A, Lotz C, Ortiz J, Lamour V. Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. (2019) Nature communications 10 (4935), 1-12
Vanden Broeck A, Mc Ewen AG, Chebaro Y, Potier N, Lamour V. Structural basis for DNA gyrase interaction with Coumermycin-A1. (2019) Journal of Medicinal Chemistry 62 (8) 4225–4231.

Bedez C, Lotz C, Batisse C, Vanden Broeck A, Stote R, Howard E, Pradeau-Aubreton K, Ruff M, Lamour V. Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain (2018) Scientific Reports 8, 9272.
Azarkan M, Feller G, Vandenameele J, Herman R, El Mahyaoui R, Sauvage E, Vanden Broeck A, Matagne A, Charlier P, Kerff F. Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem. (2018) Scientific Reports 8, 1150.

Vanden Broeck A, Van der Heiden E, Sauvage E, Dauvin M, Joris B, Duez C. A Lysine Cluster in Domain II of Bacillus subtilis PBP4a Plays a Role in the Membrane Attachment of This C1- PBP. (2015) PLoS ONE 10(10): e0140082.

updated on 10/26/25